 | "L.E.M." | Paper Soft | Paper Soft | MSX
| 1985 | - | 6800 | - | - | 1659654356Aug 05 2022 | 0Jan 01 1970 |
 | 3D Deathchase | Saberman | - | MSX
| Under development | - | 7923 | - | - | 1671909177Dec 24 2022 | 1671909688Dec 24 2022 |
 | A.M.C. Astro Marine Corps | Dinamic Software | Dinamic Software | MSX
| 1989 | 152 | 26912 | - | - | 1185667200Jul 29 2007 | 1760265531Oct 12 2025 |
 | After Burner Afterburner | SEGA | Activision | MSX
| 1988 | 217 | 23838 | - | - | 1177974000May 01 2007 | 1771163689Feb 15 2026 |
 | After the War | Dinamic Software | Dinamic Software | MSX
| 1989 | 111 | 24602 | - | 70% | 1185663600Jul 29 2007 | 1771158920Feb 15 2026 |
 | Afteroids | Made in Spain | - | MSX
| 1988 | 92 | 23509 | - | - | 1224623905Oct 21 2008 | 1375376703Aug 01 2013 |
 | Air Mission | Microjet | - | MSX
| Unknown | 56 | 12810 | - | - | 1307398757Jun 06 2011 | 1375376703Aug 01 2013 |
 | Akin 同族 | Parallax | Sunrise | MSX2
| 1995 | 327 | 19509 | - | - | 1329323873Feb 15 2012 | 1642981397Jan 23 2022 |
 | Aleste Gaiden アレスタ 外伝 | Compile | Compile | MSX2
| 1989 | 830 | 32219 | - | - | 1180303921May 27 2007 | 1671414246Dec 19 2022 |
 | Alien Attack | Volker Becker | Volker Becker | MSX
| 1985 | 21 | 16223 | - | - | 1450054064Dec 14 2015 | 1450054092Dec 14 2015 |
 | Aliens | Mr. Micro | - | MSX
| 1987 | 101 | 17237 | - | - | 1239926400Apr 17 2009 | 1752083352Jul 09 2025 |
 | Altered Beast | SEGA | Activision | MSX
| 1988 | 240 | 27653 | - | - | 1196467200Dec 01 2007 | 1752083363Jul 09 2025 |
 | Amo del Mundo | Crom | Positive | MSX
| 1990 | - | 13312 | - | - | 1154473200Aug 02 2006 | 1787695125Aug 25 2026 |
 | Amoto's Puf | SPE (Software de Programadores Españoles) | System 4 | MSX
| 1988 | 57 | 14046 | - | - | 1191888000Oct 09 2007 | 1752083374Jul 09 2025 |
 | Andrómeda | Julián Rubio | - | MSX
| 1987 | 49 | 12653 | - | - | 1301236947Mar 27 2011 | 0Jan 01 1970 |
 | Anty アンティ | Bothtec | ASCII Corporation | MSX
| 1984 | 81 | 17011 | - | - | 1154467920Aug 01 2006 | 1509576982Nov 01 2017 |
 | Arma Mortal | Majara Soft | Club Hnostar | MSX2
| 1994 | - | 13846 | - | - | 1475798400Oct 07 2016 | 1758452770Sep 21 2025 |
 | Armageddon 3D ハルマゲドン３Ｄ | MSX Tensei Kobo | - | MSX
| 2011 | - | 11138 | - | - | 1480877154Dec 04 2016 | 1480877291Dec 04 2016 |
 | Army Moves | Dinamic Software | - | MSX
| 1987 | 165 | 252478 | - | - | 1218672785Aug 14 2008 | 1427882382Apr 01 2015 |
 | Assembler Fighter アセンブラファイター
| Game Castle | - | MSX2
| 1994 | - | 10364 | - | - | 1444443162Oct 10 2015 | 1444443250Oct 10 2015 |
 | Aster Buster | Masachan Soft | - | MSX2
| 1988 | 59 | 11256 | - | - | 1341696492Jul 07 2012 | 1375376703Aug 01 2013 |
 | Asteroids Wars | Ecalius Software | - | MSX
| Under development | 25 | 21137 | - | - | 1308607941Jun 20 2011 | 0Jan 01 1970 |
 | Atlantida | Silvio Chan | CPU | MSX
| 1989 | - | 218 | - | - | 1746921600May 11 2025 | 1746982219May 11 2025 |
 | Attacked | Tynesoft | Micro Value | MSX
| Unknown | 68 | 19146 | - | - | 1223727510Oct 11 2008 | 1685412109May 30 2023 |
 | Ball Bouncer | Nerlaska Studio | - | MSX
| 2012 | - | 8033 | - | - | 1354053103Nov 27 2012 | 1375376703Aug 01 2013 |
 | Barbarian | Ford Perfect | Ford Perfect | MSX2
| 1988 | 98 | 16762 | - | - | 1176401180Apr 12 2007 | 1509543955Nov 01 2017 |
 | Batalla Espacial | Carlos López Domínguez | - | MSX
| 1986 | 44 | 14328 | - | - | 1301237400Mar 27 2011 | 0Jan 01 1970 |
 | Battle Bomber | BitBoyz | - | MSX turbo R
MSX2
| 1996 | 125 | 17486 | - | - | 1295308800Jan 18 2011 | 1746915796May 10 2025 |
 | Battle Chopper | Methodic Solutions | Methodic Solutions | MSX
| 1987 | 73 | 23763 | - | - | 1175381213Mar 31 2007 | 1600453962Sep 18 2020 |
 | Beach Story of Tako - Part I | Komeya | Komeya | MSX
| 1987 | 35 | 12291 | - | - | 1341693848Jul 07 2012 | 1427799863Mar 31 2015 |
 | Bestial Warrior | Dinamic Software | Dinamic Software | MSX
| 1989 | 97 | 21423 | - | - | 1201049603Jan 23 2008 | 1709389989Mar 02 2024 |
 | Bet your Life | Hegega | - | MSX2
| 1994 | 113 | 17073 | - | - | 1357255289Jan 03 2013 | 1375376703Aug 01 2013 |
 | Beyond the Gate of Charon | Short Program Island | - | MSX2
| 1986 | 55 | 12181 | - | - | 1183677159Jul 06 2007 | 1441406027Sep 04 2015 |
 | Beyond the Moon of Charon | Short Program Island | - | MSX2
| Unknown | 50 | 12178 | - | - | 1183673902Jul 05 2007 | 1441406471Sep 04 2015 |
 | Bifamu | Bandai | - | MSX
| 1984 | 63 | 11872 | - | - | 1163673008Nov 16 2006 | 0Jan 01 1970 |
 | Black Cyclon | Parallax | Checkmark | MSX2
| 1993 | 218 | 20541 | - | - | 1163673216Nov 16 2006 | 1642980379Jan 23 2022 |
 | Bloody Paws | G.L.L. | Matra Computer Automations | MSX
| 2005 | - | 10838 | - | - | 1354485877Dec 02 2012 | 1568245651Sep 12 2019 |
 | Blow Up! | Eurosoft | Premium III Software Distribution | MSX
| 1987 | 108 | 14780 | - | - | 1239993602Apr 17 2009 | 1712011336Apr 01 2024 |
 | Blue Warrior | Moai-Tech | Moai-Tech | MSX2
MSX2+
MSX turbo R
| 2000 | 217 | 33076 | - | - | 1163713163Nov 16 2006 | 1702249334Dec 10 2023 |
 | Bomba Loca | Javier Loyola | - | MSX
| Unknown | 30 | 15458 | - | - | 1322256763Nov 25 2011 | 1375376703Aug 01 2013 |
 | Bomber Man Bomberman | Paragon Productions | Paragon Productions | MSX2
| 1995 | 136 | 38719 | - | - | 1450390316Dec 17 2015 | 1450390924Dec 17 2015 |
 | Bomberman Battle | - | - | MSX
| 2011 | - | 184 | - | - | 1746835200May 10 2025 | 1746916683May 10 2025 |
 | Booming Boy | MSX Area | MSX Area | MSX2
| 2015 | - | 16015 | - | - | 1447291882Nov 12 2015 | 1451013921Dec 25 2015 |
 | Bounce | Methodic Solutions | - | MSX
| 1987 | 62 | 17451 | - | - | 1181515839Jun 10 2007 | 1687129116Jun 18 2023 |
 | Brivido | - | - | MSX
| Unknown | 47 | 9785 | - | - | 1178029049May 01 2007 | 0Jan 01 1970 |
 | Buddagillie 佛陀斬 | GW's Workshop | GW's Workshop | MSX
| 2018 | 51 | 15736 | - | - | 1524509010Apr 23 2018 | 1524510661Apr 23 2018 |
 | C.A.D. Capitán Arthur Dunne | Antonio Sánchez Cádiz | MSX-Extra (Magazine) | MSX
| Unknown | 48 | 23235 | - | - | 1320702045Nov 07 2011 | 1375376703Aug 01 2013 |
 | Carguero | Carlos Collado Escrig | - | MSX
| 1989 | 41 | 12464 | - | - | 1326366756Jan 12 2012 | 1375376703Aug 01 2013 |
| Castlevania | Konami | Konami | MSX2
| 1986 | - | 15796 | - | - | 1465415099Jun 08 2016 | 1465415600Jun 08 2016 |
 | Chase H.Q. | Ocean | - | MSX
| 1989 | 180 | 14925 | - | - | 1236530044Mar 08 2009 | 0Jan 01 1970 |
 | Chicken | Electric Adventures | Electric Adventures | MSX
| Unknown | - | 7711 | - | - | 1508768239Oct 23 2017 | 1508786295Oct 23 2017 |
 | Choplifter Elicottero | Dan Gorlin | - | MSX
| 1985 | 82 | 20422 | - | - | 1152742602Jul 12 2006 | 1586197959Apr 06 2020 |
 | Chopper Chopper I Choper 1 | The Bytebusters | - | MSX
| 1986 | 76 | 17374 | - | - | 1181516437Jun 11 2007 | 1375376703Aug 01 2013 |
 | Chopper 2 | Mafia Soft | - | MSX2
| Unknown | 48 | 10617 | - | - | 1347191668Sep 09 2012 | 1375376703Aug 01 2013 |
 | Chopper II | The Bytebusters | - | MSX2
| 1986 | 56 | 12961 | - | - | 1185912219Jul 31 2007 | 0Jan 01 1970 |
 | Chuka Taisen 中華大仙 Cloud Master | GA-Yume/HOT・B | GA-Yume/HOT・B | MSX2
| 1988 | 144 | 18955 | - | - | 1185912425Jul 31 2007 | 1376914429Aug 19 2013 |
 | Coaster Race | Sony | - | MSX
| 1986 | 66 | 22441 | - | - | 1152742928Jul 12 2006 | 0Jan 01 1970 |
 | Colt 36 | Topo Soft | Topo Soft | MSX
| 1987 | 44 | 14703 | - | - | 1209513600Apr 30 2008 | 1752083955Jul 09 2025 |
 | Conclave of Darklord | GW's Workshop | Matra Computer Automations | MSX
| 2021 | 1 | 10501 | - | - | 1612824374Feb 08 2021 | 1619220176Apr 24 2021 |
 | Contra Gryzor | Konami | - | MSX2
| 1989 | - | 29343 | - | - | 1196282385Nov 28 2007 | 1375376703Aug 01 2013 |
 | Corona's Spree | Amaury Calvalho | Clube MSX | MSX
| 2020 | - | 7050 | - | - | 1619218432Apr 23 2021 | 1619218534Apr 23 2021 |
 | Cosa Nostra | Opera Soft | - | MSX
| 1986 | 76 | 16268 | - | - | 1202491290Feb 08 2008 | 0Jan 01 1970 |
 | Cosmic Sheriff | Dinamic Software | Dinamic Software | MSX
| 1989 | 67 | 19230 | - | - | 1154390400Aug 01 2006 | 1752084014Jul 09 2025 |
 | Cosmic Shock Absorber | Martech | Martech | MSX
| 1986 | 56 | 14610 | - | - | 1152906573Jul 14 2006 | 1473556381Sep 11 2016 |
 | Crazy Ball クレイジーボール | MSX Tensei Kobo | - | MSX
| 2011 | - | 12614 | - | - | 1343663600Jul 30 2012 | 1480869183Dec 04 2016 |
 | Crazy Van | Luis María Getino Getino | - | MSX
| 1991 | 39 | 11828 | - | - | 1326367334Jan 12 2012 | 1375376703Aug 01 2013 |
 | Crest of the Dragon King Hades of Darkness 闇の竜王ハデスの紋章 Yami no ryu ou Hades no monshou | Casio | Casio | MSX
| 1986 | 118 | 20459 | - | - | 1164218633Nov 22 2006 | 1759063010Sep 28 2025 |
 | Cruzada | Luis Sanguino Arias | Revista Amigos del MSX | MSX
| 1986 | 44 | 15734 | - | - | 1381968000Oct 17 2013 | 1758238867Sep 19 2025 |
 | Curro Jiménez | Arcadia Software | Zigurat | MSX
| 1989 | 57 | 18127 | - | - | 1219952270Aug 28 2008 | 1775407842Apr 05 2026 |
 | Cyborg Z | Zemina | - | MSX
| 1991 | 109 | 13856 | - | - | 1312570408Aug 05 2011 | 1375376703Aug 01 2013 |
 | D-Day | System 4 | - | MSX
| 1984 | 66 | 10739 | - | - | 1209550265Apr 30 2008 | 0Jan 01 1970 |
 | Death City | Electric Adventures | Electric Adventures | MSX
| Unknown | - | 7860 | - | - | 1508768239Oct 23 2017 | 1508785939Oct 23 2017 |
 | Deep Forest ディープフォレスト | Xain | Xain | MSX2
| 1987 | 83 | 17500 | - | - | 1217534049Jul 31 2008 | 1701477356Dec 02 2023 |
 | Defcom 1 | Iber Soft | - | MSX
| 1989 | 47 | 13175 | - | - | 1175384015Apr 01 2007 | 0Jan 01 1970 |
 | Defensa del Estrecho | Luis Antonio Martínez Amago | Load 'n' Run | MSX
| 1986 | 33 | 13836 | - | - | 1413504000Oct 17 2014 | 1753655120Jul 27 2025 |
 | Demonia | Juan Morales | Juan Morales | MSX2
| 2020 | 164 | 16498 | - | - | 1593351463Jun 28 2020 | 1613781955Feb 20 2021 |
 | Demonia | Microids | Microids | MSX
| 1986 | 111 | 26143 | - | - | 1165104000Dec 03 2006 | 1752084072Jul 09 2025 |
 | Desperado Gunsmoke | Topo Soft | ERBE Software | MSX
| 1987 | 221 | 22819 | - | - | 1209254400Apr 27 2008 | 1754234496Aug 03 2025 |
 | Desperado 2 | Topo Soft | Topo Soft | MSX
| 1991 | 110 | 17422 | - | - | 1227656325Nov 25 2008 | 1377099578Aug 21 2013 |
 | Devil Zone | Uttum | - | MSX2
| 1989 | 75 | 19287 | - | - | 1218800483Aug 15 2008 | 1520784225Mar 11 2018 |
 | Docteur Galaxie | Micros MSX | - | MSX
| 1986 | 33 | 9496 | - | - | 1280442588Jul 29 2010 | 0Jan 01 1970 |
 | Dot Attack | NOP | NOP | MSX
| 2020 | 37 | 15748 | - | - | 1581174965Feb 08 2020 | 1581175021Feb 08 2020 |
 | Double Dragon 더블 드라곤 | Zemina | Zemina | MSX
| 1989 | 149 | 23527 | - | - | 1227659931Nov 26 2008 | 1377104140Aug 21 2013 |
 | Draconic Throne | GW's Workshop | GW's Workshop | MSX
| 2017 | 38 | 15882 | - | - | 1501417806Jul 30 2017 | 1679873596Mar 27 2023 |
 | Dragon Ninja Bad Dudes vs. Dragon Ninja | Imagine | Ocean | MSX
| 1988 | 144 | 18212 | - | - | 1175384210Apr 01 2007 | 1409968340Sep 06 2014 |
 | Dragon Wang | MSX Files | - | MSX
| 2005 | 86 | 12576 | - | - | 1183671959Jul 05 2007 | 0Jan 01 1970 |
 | Dragons | Alberto Orante Vegas | - | MSX
| 1988 | 41 | 11916 | - | - | 1294104108Jan 04 2011 | 0Jan 01 1970 |
 | Duck Hunt | Karoshi Corporation | - | MSX
| 2004 | - | 11600 | - | - | 1333663608Apr 05 2012 | 1375376703Aug 01 2013 |
 | Duck Out | Dro Soft | Dro Soft | MSX
| 1989 | 47 | 16988 | - | - | 1318291200Oct 11 2011 | 1752084871Jul 09 2025 |
 | Dungeon Hunter ダンジョンハンター | ASCII Corporation | ASCII Corporation | MSX
| 1991 | 70 | 18450 | - | - | 1210089396May 06 2008 | 1573776238Nov 15 2019 |
 | Elevator Action エレベーターアクション | Taito | Nidecom | MSX
| 1985 | 100 | 29539 | 1 | 85% | 1152748800Jul 13 2006 | 1752084912Jul 09 2025 |
 | Endless War
| Masaki Satoh | - | MSX
| Unknown | - | 7071 | - | - | 1341104917Jul 01 2012 | 1375376703Aug 01 2013 |
 | Ewoks and The Dandelion Warriors Wekos | Walther Miller | Walther Miller | MSX
| 1987 | 119 | 17260 | - | - | 1159135894Sep 24 2006 | 1705622253Jan 18 2024 |
 | Exterminator | The Bytebusters | - | MSX
| 1987 | 49 | 11004 | - | - | 1178040062May 01 2007 | 0Jan 01 1970 |
 | F-16 | A.F.B. | Monser | MSX
| 1985 | 20 | 10706 | - | - | 1541374740Nov 04 2018 | 1541375213Nov 04 2018 |
 | Feedback フィードバック | Tecno Soft | Tecno Soft | MSX2
| 1988 | 48 | 12314 | - | - | 1218754800Aug 15 2008 | 1780758504Jun 06 2026 |
 | Fire Hawk Thexder II | Game Arts | - | MSX2
| 1989 | 312 | 22304 | - | - | 1163783835Nov 17 2006 | 0Jan 01 1970 |
 | Fire Warrior | Electromagic Software | - | MSX
| 1991 | 12 | 11787 | - | - | 1454542848Feb 03 2016 | 1454543464Feb 03 2016 |
 | Firefox | Francisco J. Muñoz | - | MSX
| Unknown | 40 | 17873 | - | - | 1323217902Dec 07 2011 | 1375376703Aug 01 2013 |
 | Flappy Bird | Crunchworks | Crunchworks | MSX
| 2014 | - | 11924 | - | - | 1408746999Aug 22 2014 | 0Jan 01 1970 |
 | Forbidden Fruit | Krypton Force | Krypton Force | MSX
| 1985 | 47 | 13307 | - | - | 1152662400Jul 12 2006 | 20250728Aug 23 1970 |
 | Formation Z フォーメーションＺ | Jaleco | - | MSX
| 1985 | 56 | 22264 | - | - | 1159386442Sep 27 2006 | 0Jan 01 1970 |
 | Freddy Hardest en Manhattan Sur Freddy Hardest in South Manhattan Guardian Angel | Dinamic Software | Dinamic Software | MSX
| 1989 | 86 | 18721 | - | - | 1200614400Jan 18 2008 | 1752084959Jul 09 2025 |
 | Future Boy Conan 미래소년 코난 Mirae Sonyeon Conan
| Topia | - | MSX2
| 1989 | - | 9785 | - | - | 1319740029Oct 27 2011 | 1383516362Nov 03 2013 |
 | Gaki Hiki 2 Black Serenade ガキひき野郎２ ブラックセレナーデ | OB Project | OB Project | MSX2
| 1994 | 13 | 13596 | - | - | 1480980985Dec 05 2016 | 1480981170Dec 05 2016 |
 | Garyuoh Dragon King | Xain | - | MSX2
| 1987 | 79 | 10005 | - | - | 1209555116Apr 30 2008 | 1375376703Aug 01 2013 |
 | Gazzeru | Nerlaska Studio | - | MSX
| Under development | - | 11073 | - | - | 1302473271Apr 10 2011 | 1375376703Aug 01 2013 |
 | Gekiso Battle | Komeya | - | MSX2
| 1991 | 55 | 11337 | - | - | 1209370370Apr 28 2008 | 0Jan 01 1970 |
 | Ghost'n Goblins | Assembler | Assembler | MSX
MSX2
MSX2+
MSX turbo R
| 2020 | - | 17579 | - | - | 1472418213Aug 28 2016 | 1696197551Oct 01 2023 |
 | Ghost'n Goblins | Amusement Factory | - | MSX
| 2008 | 286 | 17829 | - | - | 1209629551May 01 2008 | 0Jan 01 1970 |
 | Girly Block ガーリーブロック | Telenet Japan | Telenet Japan | MSX2
| 1987 | 131 | 25351 | - | - | 1196281865Nov 28 2007 | 1406155221Jul 23 2014 |
 | Green Beret グリーンベレー Rush'n Attack | Konami | Konami | MSX
| 1986 | - | 19450 | - | - | 1235779200Feb 28 2009 | 1752085061Jul 09 2025 |
 | Grey Wolf | Oniric Factor | Oniric Factor | MSX2
| 2017 | - | 11783 | - | - | 1503354216Aug 21 2017 | 1701822153Dec 06 2023 |
 | Grid Trap | Livewire | - | MSX
| 1985 | 47 | 12683 | - | - | 1223727510Oct 11 2008 | 1375376703Aug 01 2013 |
 | Grid Wars | Emma Six | - | MSX
| 2006 | 58 | 15084 | - | - | 1169710169Jan 25 2007 | 0Jan 01 1970 |
| Guerre Stellari | Paper Soft | Paper Soft | MSX
| 1985 | - | 6985 | - | - | 1659650283Aug 04 2022 | 1659653414Aug 04 2022 |
 | Gun Smoke Gun.Smoke | Prosoft | Prosoft | MSX
| 1990 | 281 | 28001 | - | - | 1427065040Mar 22 2015 | 1427400706Mar 26 2015 |
 | Gunstreet | Electromagic Software | Electromagic Software | MSX
| 1993 | 69 | 12927 | - | - | 1285717567Sep 29 2010 | 1450048940Dec 13 2015 |
 | HT-40 | Eugenio Garrido Gómez | Revista Amigos del MSX | MSX
| 1986 | 42 | 11448 | - | - | 1382040561Oct 17 2013 | 1382041453Oct 17 2013 |
 | Hammer Boy | Dinamic Software | Dinamic Software | MSX
| 1991 | 69 | 12538 | - | - | 1223683200Oct 11 2008 | 1752085106Jul 09 2025 |
| Hammer-Head
| Zigurat | Zigurat | MSX
| 1992 | - | 8795 | - | - | 1396467727Apr 02 2014 | 1396468077Apr 02 2014 |
 | Heli War | PISC Soft | - | MSX
| 1987 | - | 197 | - | - | 1746316800May 04 2025 | 1746323641May 04 2025 |
 | Helitank | Nabu
ASCII Corporation | - | MSX
| 1984 | 51 | 13344 | - | - | 1158088718Sep 12 2006 | 0Jan 01 1970 |
 | Hundra | Zeus Software | Dinamic Software | MSX
| 1988 | 101 | 27429 | - | - | 1219881600Aug 28 2008 | 1755124515Aug 13 2025 |
 | Hyper Soldier Angel ハイパー兵士の天使 HSA | Relevo Videogames | Relevo Videogames | MSX
| Unreleased | - | 12215 | - | - | 1303847732Apr 26 2011 | 1510698805Nov 14 2017 |
 | Ice | The Bytebusters | - | MSX
| 1986 | 75 | 13543 | - | - | 1153410473Jul 20 2006 | 1375376703Aug 01 2013 |
 | Iga Ninpo Chou 伊賀忍法帖 Notebook of Iga's Technique | Casio | Casio | MSX
| 1985 | 107 | 17106 | - | - | 1217447728Jul 30 2008 | 1377213159Aug 23 2013 |
 | Ikari Ikari Warriors | SNK | - | MSX2
| 1987 | 184 | 20704 | - | - | 1209555378Apr 30 2008 | 0Jan 01 1970 |
 | Intruder イントルーダー
| Yasushi Enari | POPCOM (ポプコム) | MSX
| 1985 | - | 9589 | - | - | 1399807498May 11 2014 | 0Jan 01 1970 |
 | Invasion | Sherif Hashim | - | MSX
| 2011 | 49 | 11361 | - | - | 1307134305Jun 03 2011 | 0Jan 01 1970 |
 | Invasion of the Zombie Monsters | Relevo Videogames | - | MSX
| 2010 | - | 14904 | - | - | 1275523200Jun 03 2010 | 1752087374Jul 09 2025 |
 | Invasión intergaláctica Invasión | Antonio Montero | - | MSX
| Unknown | 21 | 7998 | - | - | 1321655263Nov 18 2011 | 1375376703Aug 01 2013 |
| Iron Horse | Konami | Konami | MSX
| Unreleased | - | 134 | - | - | 1783457870Jul 07 2026 | 1783458253Jul 07 2026 |
 | Jailbreak | Infinite | - | MSX2
| 2010 | 113 | 16438 | - | - | 1278109719Jul 02 2010 | 0Jan 01 1970 |
 | Jaw Breaker II | Maggoo | Maggoo | MSX
| 2014 | - | 10073 | - | - | 1402503993Jun 11 2014 | 0Jan 01 1970 |
 | Jet-Monster | - | - | MSX
| 1985 | 38 | 11714 | - | - | 1307137696Jun 03 2011 | 0Jan 01 1970 |
 | Jet-Monster | - | - | MSX
| Unknown | 45 | 11403 | - | - | 1350234933Oct 14 2012 | 1375376703Aug 01 2013 |
 | Joust | Mystery Man | Repro Factory MSX Shop | MSX
| 2017 | - | 10408 | - | - | 1488584138Mar 03 2017 | 1515110237Jan 04 2018 |
 | Juega... pero seguro | OMK Software | - | MSX
| 1989 | 55 | 14956 | - | - | 1223727510Oct 11 2008 | 1375376703Aug 01 2013 |
 | Juegue con su MSX Nº 2 - Alpha Centauro Alpha Centauro | Grupo de Trabajo Software | - | MSX
| 1987 | 52 | 13814 | - | - | 1343431301Jul 28 2012 | 1375376703Aug 01 2013 |
 | Jump | Zigurat | Zigurat | MSX
| 1992 | 56 | 12558 | - | - | 1396462063Apr 02 2014 | 1775408037Apr 05 2026 |
 | Jungle Warrior | True Software | Zigurat | MSX
| 1990 | 71 | 18046 | - | - | 1230854400Jan 02 2009 | 1775408173Apr 05 2026 |
 | Junker Squad | Trash
Hegega | - | MSX2
| 1994 | - | 8561 | - | - | 1347210863Sep 09 2012 | 1375376703Aug 01 2013 |
 | Kensei 2 | Salami | - | MSX2
| Unknown | 35 | 10852 | - | - | 1209372934Apr 28 2008 | 0Jan 01 1970 |
 | Killer Station キラーステーション | Hudson Soft | Hudson Soft | MSX
| 1983 | - | 10030 | - | - | 1223727510Oct 11 2008 | 1586046828Apr 05 2020 |
 | King & Balloon キング＆バルーン | Namco | Namco | MSX
| 1984 | 76 | 13783 | - | - | 1159574400Sep 30 2006 | 1755820696Aug 22 2025 |
| Kingfisher | Infinite | - | MSX
| Under development | - | 6729 | - | - | 1354471932Dec 02 2012 | 1375376703Aug 01 2013 |
 | Knightmare 魔城伝説 Attila | Konami | Konami | MSX
| 1985 | - | 36045 | 1 | - | 1186012800Aug 02 2007 | 1775402626Apr 05 2026 |
 | Krom - El Guerrero | OMK Software | Proein Softline | MSX
| 1989 | 55 | 11858 | - | - | 1318723200Oct 16 2011 | 1755997021Aug 24 2025 |
 | Krypton | Manhattan Transfer | Manhattan Transfer | MSX
| 1985 | 41 | 15973 | - | - | 1252627200Sep 11 2009 | 1755997463Aug 24 2025 |
 | LEDA | John Hassink
Paco Santos Ramírez | - | MSX2
| 2008 | 47 | 12012 | - | - | 1230329417Dec 26 2008 | 0Jan 01 1970 |
 | La Espada Sagrada | Topo Soft | ERBE Software | MSX
| 1990 | 73 | 19845 | - | - | 1159136031Sep 24 2006 | 1377109384Aug 21 2013 |
 | La Venganza de Johny Comomolo | Juliet Software | Dro Soft | MSX
| 1986 | - | 10241 | - | - | 1175727600Apr 05 2007 | 1783703110Jul 10 2026 |
 | Laser Battle Lazer Battle | Robtek Software | Robtek Software | MSX
| 1986 | 1 | 2465 | - | - | 1701866760Dec 06 2023 | 1701867539Dec 06 2023 |
 | Liberator Contra | PJ Soft | - | MSX
| 1989 | 67 | 11658 | - | - | 1355096750Dec 09 2012 | 1375376703Aug 01 2013 |
 | Life on Earth | Kai Magazine | Kai Magazine | MSX2
| 2018 | - | 30978 | - | - | 1518133780Feb 08 2018 | 1534706568Aug 19 2018 |
 | Life on Mars | Kai Magazine | Kai Magazine | MSX2
MSX2+
MSX turbo R
| 2015 | - | 22902 | - | - | 1446731263Nov 05 2015 | 1518134098Feb 08 2018 |
 | Lorna | Topo Soft | ERBE Software | MSX
| 1990 | 71 | 19354 | - | - | 1203465600Feb 20 2008 | 1756058545Aug 24 2025 |
 | Los Inhumanos | Delta Software | - | MSX
| 1990 | 48 | 11114 | - | - | 1318374925Oct 12 2011 | 0Jan 01 1970 |
 | M-47 Combate de blindados | Edisoft | - | MSX
| 1986 | 53 | 11647 | - | - | 1343430212Jul 28 2012 | 1375376703Aug 01 2013 |
 | MASK II | Gremlin Graphics | - | MSX
| 1987 | 63 | 15203 | - | - | 1175781913Apr 05 2007 | 1375376703Aug 01 2013 |
 | MSX Edisoft Nº6 - Olegario, El Policía de mi Barrio | Edisoft | Edisoft | MSX
| 1987 | - | 9849 | - | - | 1545005823Dec 17 2018 | 20250414Aug 23 1970 |
 | MSX Games Nº 5 - Patrullera XH-63 | Genesis Soft | Grupo de Trabajo Software | MSX
| 1986 | 66 | 14721 | - | - | 1223727510Oct 11 2008 | 1375376703Aug 01 2013 |
 | MSX Software Nº 12 - Phantom en Ataque Phantom Ataca | Ángel García Delgado | Grupo de Trabajo Software | MSX
| 1986 | 20 | 13144 | - | - | 1541721600Nov 09 2018 | 1757796075Sep 13 2025 |
 | MSX Software Nº 14 - Super Piloto Piloto | Grupo de Trabajo Software | Grupo de Trabajo Software | MSX
| Unknown | - | 8824 | - | - | 1541721600Nov 09 2018 | 1757796508Sep 13 2025 |
 | MSX Software Nº 21 - Tank Attack Death House | Grupo de Trabajo Software | Grupo de Trabajo Software | MSX
| Unreleased | 1 | 232 | - | - | 1757548800Sep 11 2025 | 1757797685Sep 13 2025 |
 | MSX Video-Play #2 - Miki el esquiador Miki va a esquiar | Ángel García Delgado | P.P.P. Ediciones | MSX
| Unknown | 20 | 14578 | - | - | 1364516013Mar 29 2013 | 1472866585Sep 03 2016 |
| Makaimura 魔界村 Ghosts'n Goblins | Capcom | Capcom | MSX
MSX2
| Unreleased | - | 12173 | - | - | 1365075705Apr 04 2013 | 1375376703Aug 01 2013 |
 | Mambo | Positive | Positive | MSX
| 1989 | 47 | 13741 | - | - | 1243468800May 28 2009 | 1757113641Sep 06 2025 |
 | Mazes Unlimited | Aackosoft | - | MSX
| 1986 | 50 | 14825 | - | - | 1333714076Apr 06 2012 | 1375376703Aug 01 2013 |
 | Mekong Mecom | Iber Soft | Iber Soft | MSX
| 1988 | 2 | 2775 | - | - | 1714592527May 01 2024 | 1714593998May 01 2024 |
 | Menace | The New Image (TNI) | - | MSX
| 2009 | 63 | 12608 | - | - | 1293405188Dec 26 2010 | 0Jan 01 1970 |
 | Metropolis | Topo Soft | ERBE Software | MSX
| 1989 | 80 | 18524 | - | - | 1225584000Nov 02 2008 | 1757272478Sep 07 2025 |
 | Midway カラー・ミッドウエイ | Magic Soft | - | MSX
| 1983 | 54 | 14894 | - | - | 1159606887Sep 30 2006 | 1375376703Aug 01 2013 |
 | Mike Gunner | Dinamic Software | - | MSX
| 1988 | 55 | 10682 | - | - | 1223683200Oct 11 2008 | 1757271986Sep 07 2025 |
 | Mini Snafu | Giovanni Nunes | Clube MSX | MSX
| 2020 | - | 6332 | - | - | 1619218068Apr 23 2021 | 1619218384Apr 23 2021 |
 | MiniMagos | unepic fran | unepic fran | MSX
| 2017 | - | 12594 | - | - | 1506554290Sep 28 2017 | 1506554357Sep 28 2017 |
 | Miraculus | Volker Becker | Volker Becker | MSX
| 1985 | 48 | 12618 | - | - | 1144256203Apr 05 2006 | 1450053648Dec 14 2015 |
 | Misión imposible | - | - | MSX
| Unknown | 38 | 11767 | - | - | 1343516186Jul 28 2012 | 1375376703Aug 01 2013 |
 | Missile Command | Electric Adventures | Electric Adventures | MSX
| Unknown | - | 9149 | - | - | 1508768239Oct 23 2017 | 1508774446Oct 23 2017 |
| Missione su Zircon | Paper Soft | Paper Soft | MSX
| 1985 | - | 6555 | - | - | 1659652673Aug 04 2022 | 1659653102Aug 04 2022 |
 | Mithos Mythos | Comix
Opera Soft | Opera Soft | MSX
| 1990 | 82 | 18333 | - | - | 1219881600Aug 28 2008 | 1757817093Sep 14 2025 |
 | Mon Mon Monster 悶々怪物 Mon Mon Kaibutsu | HOT•B | HOT•B | MSX2
| 1989 | 125 | 25574 | - | - | 1176336000Apr 12 2007 | 1752091876Jul 09 2025 |
 | Monster's Fair | Toho | - | MSX
| 1984 | 81 | 14425 | - | - | 1159833600Oct 03 2006 | 1752091887Jul 09 2025 |
 | Moon Race | Volker Becker | Volker Becker | MSX
| 1985 | 46 | 10742 | - | - | 1223727510Oct 11 2008 | 1450116044Dec 14 2015 |
 | Morning Star | GW's Workshop | GW's Workshop | MSX2
| 1997 | 67 | 15597 | - | - | 1415578510Nov 10 2014 | 1541070693Nov 01 2018 |
 | Motorbike Madness | Mastertronic | Dro Soft | MSX
| 1988 | 24 | 11893 | - | - | 1489782472Mar 17 2017 | 1489783099Mar 17 2017 |
 | Mountain Game | M. Kobayashi | - | MSX
| 1986 | 44 | 10670 | - | - | 1415582229Nov 10 2014 | 1450356453Dec 17 2015 |
 | Mr. Cracksman | Relevo Videogames | Relevo Videogames | MSX
| 2013 | - | 11301 | - | - | 1380833934Oct 03 2013 | 1402680930Jun 13 2014 |
 | Mutan Zone | Opera Soft | Opera Soft | MSX
| 1988 | 61 | 13967 | - | - | 1177977600May 01 2007 | 1757814698Sep 14 2025 |
 | Mutant Monty | Artic Computing | Artic Computing | MSX
| 1985 | 75 | 14087 | - | - | 1175731200Apr 05 2007 | 1757538596Sep 10 2025 |
 | Mystical | Infogrames | ERBE Software | MSX
| 1991 | 67 | 13564 | - | - | 1303776000Apr 26 2011 | 1757816356Sep 14 2025 |
 | Myth and Dragons | Kai Magazine | Kai Magazine | MSX2
| 2017 | - | 13977 | - | - | 1506468363Sep 27 2017 | 1515111177Jan 05 2018 |
 | N-Sub | SEGA | - | MSX
| 1988 | 74 | 11599 | - | - | 1279236813Jul 16 2010 | 1375376703Aug 01 2013 |
 | NLAW | Nick Shcherbyna | BASIC 10 Liner Contest | MSX
| 2022 | 1 | 224 | - | - | 1746835200May 10 2025 | 1746914134May 10 2025 |
 | Navy Moves | Dinamic Software | Dinamic Software | MSX
| 1988 | 114 | 15973 | - | - | 1196208000Nov 28 2007 | 1757820992Sep 14 2025 |
 | Nebula Wars | Juan Carlos Enrique Forcada | - | MSX
| 1989 | 38 | 11162 | - | - | 1194910930Nov 12 2007 | 1375376703Aug 01 2013 |
| Ned's Trick or Treat Bizarre Odyssey - Invasion of the Zombie Monsters 2 | Relevo Videogames | - | MSX
| Unreleased | - | 9858 | - | - | 1477931059Oct 31 2016 | 1477931174Oct 31 2016 |
 | New Chikuwa Watch New ちくわウォッチ | Chikuwa Teikoku | Chikuwa Teikoku | MSX
| 2023 | 1 | 2867 | - | - | 1695426747Sep 23 2023 | 1695427203Sep 23 2023 |
 | New York Kung-Fu 1987 | 6502man | 6502man | MSX2
| Under development | - | 10506 | - | - | 1539616002Oct 15 2018 | 1539616088Oct 15 2018 |
 | Ninfas 2 | Kotai | Kotai | MSX
| 2011 | 70 | 15920 | - | - | 1295381760Jan 18 2011 | 1587947531Apr 27 2020 |
 | Ninja Princess 忍者プリンセス | Pony Canyon | SEGA | MSX
| 1986 | 66 | 15014 | - | - | 1143500400Mar 28 2006 | 1781920545Jun 20 2026 |
 | Ninja Savior 忍者救世主 | Relevo Videogames | Relevo Videogames | MSX
| 2015 | - | 14457 | - | - | 1448755200Nov 29 2015 | 1752092968Jul 09 2025 |
 | Ninja Savior + Mr. Cracksman | Relevo Videogames | Matra Computer Automations | MSX
| 2015 | - | 8730 | - | - | 1449442824Dec 06 2015 | 1449443157Dec 06 2015 |
 | No Name Sin Nombre Ninjinkun 2 | Kai Magazine | Kai Magazine | MSX2
| 1996 | - | 14576 | - | - | 1357913392Jan 11 2013 | 1751674344Jul 05 2025 |
 | Nuclear Invaders | Dani Crespo | - | MSX
| 2012 | 51 | 18355 | - | - | 1356483169Dec 26 2012 | 1375376703Aug 01 2013 |
 | Objetivo: Nueva York | - | - | MSX
| 1985 | 43 | 11591 | - | - | 1292535245Dec 16 2010 | 0Jan 01 1970 |
 | Obliterator | Animagic | Melbourne House | MSX
| 1989 | 56 | 12575 | - | - | 1175727600Apr 05 2007 | 1771170684Feb 15 2026 |
 | One Arm
| License | - | MSX
| Unknown | - | 8238 | - | - | 1341695792Jul 07 2012 | 1375376703Aug 01 2013 |
 | Operation Name: Crossbow | Karoshi Corporation | - | MSX
| Unreleased | 67 | 15187 | - | - | 1302279968Apr 08 2011 | 0Jan 01 1970 |
 | Operation Wolf | Toybox | MSXdev contest | MSX
| 2006 | 176 | 26079 | - | - | 1223067970Oct 03 2008 | 1702250503Dec 10 2023 |
 | Operation Wolf Berretti Verdi | Ocean | - | MSX
| 1988 | 102 | 18809 | - | - | 1228960883Dec 11 2008 | 1712006197Apr 01 2024 |
 | Orguss | MSX Files | - | MSX
| Unknown | 74 | 12066 | - | - | 1227102948Nov 19 2008 | 0Jan 01 1970 |
 | Pang! | M. Louvet | M. Louvet | MSX
| 2015 | - | 10409 | - | - | 1425129291Feb 28 2015 | 1425129387Feb 28 2015 |
| Penguin Race | Dioniso | - | MSX
| 2003 | 60 | 12390 | - | - | 1219680335Aug 25 2008 | 0Jan 01 1970 |
 | Phantis Game Over II Game Over 2 | Dinamic Software | Dinamic Software | MSX
| 1987 | 131 | 16873 | - | - | 1177977600May 01 2007 | 20250731Aug 23 1970 |
 | Phnom Penh 民衆１万人大虐殺ゲーム・プノンペン | OSTS | OSTS | MSX turbo R
| 1997 | - | 5936 | - | - | 1672082379Dec 26 2022 | 1672082649Dec 26 2022 |
 | Phobos | Attackersoft | Attackersoft | MSX
MSX2
| 1990 | 77 | 13547 | - | - | 1209339588Apr 28 2008 | 1375376703Aug 01 2013 |
 | Phoenix
| Masaki Satoh | - | MSX
| 1984 | - | 7521 | - | - | 1341105317Jul 01 2012 | 1375376703Aug 01 2013 |
 | Piso Zero | Zigurat | - | MSX
| 1991 | 59 | 12961 | - | - | 1158519732Sep 17 2006 | 1775408289Apr 05 2026 |
 | Planet Attack | - | - | MSX
| Unknown | 32 | 10435 | - | - | 1322395877Nov 27 2011 | 1375376703Aug 01 2013 |
 | Pointless Shooting | The New Image (TNI) | - | MSX
| 2006 | 30 | 9713 | - | - | 1169683200Jan 25 2007 | 1746961107May 11 2025 |
 | Police Academy | The Bytebusters | - | MSX
| 1987 | 54 | 26440 | - | - | 1175784516Apr 05 2007 | 1375376703Aug 01 2013 |
 | Police Academy II | Methodic Solutions | Methodic Solutions | MSX
| 1987 | 54 | 17122 | - | - | 1159603426Sep 30 2006 | 1702333609Dec 11 2023 |
 | Power Magic Power and Magic | Gamesoft | Zigurat | MSX
| 1990 | 54 | 13506 | - | - | 1144942048Apr 13 2006 | 1701814158Dec 05 2023 |
 | Pretty Kingdom | Nerlaska Studio | Nerlaska Studio | MSX
| 2014 | - | 11337 | - | - | 1382913352Oct 27 2013 | 1402869253Jun 15 2014 |
 | Psycho Pigs / Titanic | Topo Soft
U.S. Gold | IBSA | MSX
| 1988 | - | 215 | - | - | 1781996400Jun 21 2026 | 1782072454Jun 21 2026 |
 | Psycho World サイコワールド | Hertz | Hertz | MSX2
| 1988 | 504 | 25796 | - | - | 1196208000Nov 28 2007 | 1780764141Jun 06 2026 |
 | R.A.M. | Topo Soft | - | MSX
| 1990 | 61 | 17321 | - | - | 1196554171Dec 02 2007 | 1375376703Aug 01 2013 |
 | Rabbit Walk | Volker Becker | Volker Becker | MSX
| 1985 | 21 | 11032 | - | - | 1450117121Dec 14 2015 | 1450117330Dec 14 2015 |
 | Race City | Genesis Soft | Iber Soft | MSX
| 1988 | 57 | 14257 | - | - | 1218754800Aug 15 2008 | 1774661626Mar 28 2026 |
 | Raid over Coin | Marcos Fajardo Orellana | - | MSX
| 1987 | 39 | 11751 | - | - | 1320704319Nov 07 2011 | 1375376703Aug 01 2013 |
 | Rastan Saga ラスタンサーガ | Taito | Taito | MSX2
| 1988 | 121 | 116759 | - | - | 1196285323Nov 28 2007 | 1403965442Jun 28 2014 |
 | RasterScan Raster Scan | - | Mastertronic | MSX
| 1987 | 50 | 18836 | - | - | 1155164400Aug 10 2006 | 1774196319Mar 22 2026 |
 | Renegade III - The Final Chapter | Imagine | ERBE Software | MSX
| 1989 | 80 | 17324 | - | - | 1153782000Jul 25 2006 | 1771174562Feb 15 2026 |
 | River Chase リバーチェイス
| Soft Pro International | Soft Pro International | MSX
| 1985 | - | 10683 | - | - | 1472861881Sep 03 2016 | 1472862114Sep 03 2016 |
 | River Raid | Activision | Activision | MSX
| 1984 | 120 | 18917 | - | 77% | 1196285868Nov 28 2007 | 20250617Aug 23 1970 |
 | Robocop RoboCop | Ocean | Ocean | MSX
| 1989 | 294 | 69724 | - | 75% | 1215298800Jul 06 2008 | 1771176244Feb 15 2026 |
| Robot | Paper Soft | Paper Soft | MSX
| 1985 | - | 6117 | - | - | 1659652990Aug 04 2022 | 0Jan 01 1970 |
 | Robot Wars | Aackosoft | - | MSX
| 1986 | 97 | 30231 | - | - | 1154469143Aug 01 2006 | 1375376703Aug 01 2013 |
 | Rock City | - | - | MSX2
| 1995 | 46 | 12948 | - | - | 1284072841Sep 09 2010 | 1450399587Dec 18 2015 |
 | Rock'n Roller | Topo Soft | - | MSX
| 1988 | 72 | 13733 | - | - | 1224026082Oct 15 2008 | 1375376703Aug 01 2013 |
 | Rocket | - | - | MSX
| Unknown | 42 | 12464 | - | - | 1355650409Dec 16 2012 | 1375376703Aug 01 2013 |
 | Rona | Dixie | - | MSX2
| 1994 | 69 | 25015 | - | - | 1194908448Nov 12 2007 | 0Jan 01 1970 |
 | Ruta-X | Luis Sanguino Arias | Revista Amigos del MSX | MSX
| 1986 | 42 | 11278 | - | - | 1382037020Oct 17 2013 | 1382038446Oct 17 2013 |
| S.T.G. Special - Do Dontaku | Y. Tomohara | - | MSX turbo R
| 1988 | 78 | 13680 | - | - | 1260483738Dec 10 2009 | 0Jan 01 1970 |
 | S.U.E.R.T.E. Bruce Suerte Bruce! | Scorpio Software | Input MSX (Magazine) | MSX
| 1986 | 45 | 10667 | - | - | 1350332868Oct 15 2012 | 1706562718Jan 29 2024 |
 | SD Amiga | Hegega
S.T.U.F.F. | - | MSX2
| Unknown | - | 7814 | - | - | 1347213165Sep 09 2012 | 1375376703Aug 01 2013 |
 | SKULLrs | Digital Concrete | Digital Concrete | MSX
| 2017 | - | 9691 | - | - | 1483919068Jan 08 2017 | 1484089206Jan 10 2017 |
 | Sabrina | Genesis Soft | MCM Software | MSX
| 1989 | 76 | 12951 | - | - | 1154649600Aug 04 2006 | 1752094932Jul 09 2025 |
 | Saratoga | Revista Amigos del MSX | Revista Amigos del MSX | MSX
| 1986 | 19 | 10950 | - | - | 1426451192Mar 15 2015 | 0Jan 01 1970 |
 | Satán Satan | Dinamic Software | Dinamic Software | MSX
| 1989 | 61 | 34998 | - | - | 1225658297Nov 02 2008 | 1377697085Aug 28 2013 |
 | Satélite Espacial | Javier Benito | - | MSX
| 1985 | 43 | 11568 | - | - | 1350225251Oct 14 2012 | 1375376703Aug 01 2013 |
 | Scarlet 7 | Toshiba-EMI Ltd. | - | MSX
| 1986 | 54 | 14058 | - | - | 1159564417Sep 29 2006 | 0Jan 01 1970 |
| Sea Harrier | Paper Soft | Paper Soft | MSX
| 1985 | - | 6232 | - | - | 1659567600Aug 04 2022 | 1775414311Apr 05 2026 |
 | Sea Hunter | Spectravideo | - | MSX
| 1985 | 44 | 12265 | - | - | 1159862610Oct 03 2006 | 0Jan 01 1970 |
 | Sea King | Hardip Mothada | Players | MSX
| 1986 | 66 | 13488 | - | - | 1154515393Aug 02 2006 | 1693521487Aug 31 2023 |
 | Seiken Acho 聖拳アチョー Kung-Fu Acho Taekwon-do | Irem
ASCII Corporation | ASCII Corporation | MSX
| 1985 | 129 | 18371 | 1 | 81% | 1220225522Sep 01 2008 | 1759345893Oct 01 2025 |
 | Senda Salvaje | Gamesoft | Zigurat | MSX
| 1990 | 49 | 11848 | - | - | 1152030772Jul 04 2006 | 1775408342Apr 05 2026 |
 | Sex Bomb Bunny | Matra Computer Automations | Matra Computer Automations | MSX2
| 1999 | - | 13266 | - | - | 1209513600Apr 30 2008 | 20250705Aug 23 1970 |
| Shinobi | Fudeba | - | MSX
| 2004 | 68 | 17207 | - | - | 1175792251Apr 05 2007 | 1375376703Aug 01 2013 |
 | Shinobi | Virgin Mastertronic | - | MSX
| 1989 | 97 | 13767 | - | - | 1249819417Aug 09 2009 | 0Jan 01 1970 |
 | Shoot the Flying Windows | NYYRIKKI | - | MSX turbo R
| 1997 | - | 10995 | - | - | 1166520641Dec 19 2006 | 1600614300Sep 20 2020 |
 | Shooter-X | T. Murakami | T. Murakami | MSX
| 1993 | 62 | 17248 | - | - | 1165221908Dec 04 2006 | 1454541644Feb 03 2016 |
 | Shooting Star | GW's Workshop | GW's Workshop | MSX2
| 1996 | 28 | 11375 | - | - | 1492340517Apr 16 2017 | 1492340973Apr 16 2017 |
 | Shouganai しょうがない | Paxanga Software | Paxanga Software | MSX
| 2013 | - | 11867 | - | - | 1371600000Jun 19 2013 | 20250820Aug 23 1970 |
 | Shoulder Blade OUTERSPACE | GW's Workshop | Matra Computer Automations | MSX
| 2019 | - | 9783 | - | - | 1572814759Nov 03 2019 | 1595539260Jul 23 2020 |
 | Shoulder Blade OVERDRIVE | GW's Workshop | GW's Workshop | MSX2
| 2018 | 50 | 19369 | - | - | 1539525637Oct 14 2018 | 1581176239Feb 08 2020 |
 | Singo | N.I. | N.I. | MSX
| Unknown | 37 | 23887 | - | - | 1302377138Apr 09 2011 | 1471038481Aug 12 2016 |
| Sink King | Guzuta Raster Leisure | - | MSX
| 2004 | 48 | 9614 | - | - | 1219622400Aug 25 2008 | 1760810708Oct 18 2025 |
 | Skram Omega | Humberto Martínez Barberá | - | MSX
| 1986 | 42 | 11708 | - | - | 1320683467Nov 07 2011 | 1375376703Aug 01 2013 |
 | Skramble Adonis | Aackosoft
Livewire | Livewire | MSX
| 1984 | 68 | 14426 | - | - | 1223679600Oct 11 2008 | 1776627453Apr 19 2026 |
 | Smaily | NF Stars | Zigurat | MSX
| 1990 | 54 | 13665 | - | - | 1159570800Sep 30 2006 | 1776888561Apr 22 2026 |
 | Sol Negro Bully | Opera Soft | Opera Soft | MSX
| 1988 | 100 | 28078 | - | - | 1201737600Jan 31 2008 | 1777156484Apr 25 2026 |
 | Solaris | Volker Becker | Volker Becker | MSX
| 1985 | 25 | 12842 | - | - | 1450117947Dec 14 2015 | 1450118197Dec 14 2015 |
 | Soldier of Light | Softek International | Dro Soft | MSX
| 1989 | 54 | 12048 | - | - | 1159138800Sep 25 2006 | 1777156524Apr 25 2026 |
 | Soviet | Opera Soft | Opera Soft | MSX
| 1990 | 74 | 14309 | - | - | 1159311600Sep 27 2006 | 1777156374Apr 25 2026 |
 | Space Harrier | Piroyan Soft | - | MSX
| Unreleased | - | 10978 | - | - | 1576929795Dec 21 2019 | 1576929927Dec 21 2019 |
 | Space Harrier II Space Harrier 2 | Grandslam Entertainments | Grandslam Entertainments | MSX
| 1990 | - | 13385 | - | - | 1318809133Oct 17 2011 | 1755132756Aug 14 2025 |
 | Space Invaders | Electric Adventures | Electric Adventures | MSX
| Unknown | - | 8220 | - | - | 1508767815Oct 23 2017 | 1508767815Oct 23 2017 |
| Space Invaders Collection | Ricardo Bittencourt | - | MSX
| 2002 | 185 | 21956 | - | - | 1279144790Jul 14 2010 | 0Jan 01 1970 |
 | Space Rescue | The Bytebusters | Eaglesoft | MSX
| 1986 | 58 | 16397 | - | - | 1154905200Aug 07 2006 | 1778366218May 09 2026 |
 | Spade Carrier | - | - | MSX
| Unreleased | - | 11063 | - | - | 1576931161Dec 21 2019 | 1576932116Dec 21 2019 |
 | Spring Warrior | Oniric Factor | Oniric Factor | MSX2
| 2016 | - | 11943 | - | - | 1454419619Feb 02 2016 | 1463603511May 18 2016 |
 | Star Bowls | Diabolic Software | Zigurat | MSX
| 1991 | 18 | 15454 | - | - | 1309647600Jul 03 2011 | 1778451049May 10 2026 |
 | Star Fighter | The Bytebusters | Aackosoft | MSX
| 1986 | 49 | 15114 | - | - | 1223679600Oct 11 2008 | 1778455187May 11 2026 |
 | Star Jacker | MSX Files | - | MSX
| 2004 | 84 | 12910 | - | - | 1227103789Nov 19 2008 | 0Jan 01 1970 |
 | Star Wars Space War | Frederic Markus | - | MSX
| 1985 | 61 | 10932 | - | - | 1289952000Nov 17 2010 | 1778495302May 11 2026 |
 | Star Wars | The Bytebusters | Eaglesoft | MSX
| 1986 | - | 15769 | - | - | 1154386800Aug 01 2006 | 1778493442May 11 2026 |
 | Starbite | Eurosoft | Eurosoft | MSX
| 1988 | 32 | 10551 | - | - | 1600383600Sep 18 2020 | 1778450189May 10 2026 |
 | Starbuggy | Eurosoft | Eurosoft | MSX
| 1988 | 36 | 12217 | - | - | 1176505200Apr 14 2007 | 1778451927May 10 2026 |
 | Starbyte | Mister Chip | Mister Chip | MSX
| 1987 | 47 | 11591 | - | - | 1155225379Aug 10 2006 | 1506551932Sep 27 2017 |
 | Stop Ball | Juliet Software | Dro Soft | MSX
| 1987 | - | 11768 | - | - | 1159052400Sep 24 2006 | 1778537811May 11 2026 |
 | Sub Battle | Julio César Aldariz | - | MSX
| Unknown | 34 | 9963 | - | - | 1350265968Oct 15 2012 | 1375376703Aug 01 2013 |
 | Submarino Aventurero | Diego García Martínez | - | MSX
| 1987 | 37 | 12413 | - | - | 1326362680Jan 12 2012 | 1375376703Aug 01 2013 |
 | Sudden Burst | Víctor Marzo
David Martínez Armesto (atrusyan) | David Martínez Armesto (atrusyan) | MSX2
| 2021 | - | 12047 | - | - | 1485964450Feb 01 2017 | 1641158870Jan 02 2022 |
 | Super Heli | Michel Janssen | - | MSX
| Unknown | 34 | 9567 | - | - | 1241224834May 02 2009 | 0Jan 01 1970 |
 | Super Suwanggi Super 수왕기 Super Altered Beast | Clover | Clover | MSX
| 1990 | 76 | 14437 | - | - | 1297896400Feb 16 2011 | 1441416867Sep 05 2015 |
 | Superman | Tynesoft | - | MSX
| 1988 | 73 | 16230 | - | - | 1305326993May 13 2011 | 0Jan 01 1970 |
 | TNT | Infogrames | - | MSX2
| 1987 | 89 | 12777 | - | - | 1195382659Nov 18 2007 | 0Jan 01 1970 |
 | Tank | N.I. | N.I. | MSX2
| 1997 | 53 | 12487 | - | - | 1302377550Apr 09 2011 | 1471037201Aug 12 2016 |
 | Target Plus | Dinamic Software | Dinamic Software | MSX
| 1988 | - | 18956 | - | - | 1158361200Sep 16 2006 | 1779050041May 17 2026 |
 | Tatakare Mogura
| - | - | MSX2
| 1990 | - | 6911 | - | - | 1341694783Jul 07 2012 | 1375376703Aug 01 2013 |
 | Teenage Mutant Ninja Turtles Tortugas Ninja | Image Works | MCM Software | MSX
| 1990 | 171 | 33964 | - | - | 1195603200Nov 21 2007 | 1783249562Jul 05 2026 |
 | Teenage Mutant Ninja Turtles | Ricardo Bittencourt | - | MSX turbo R
| Under development | - | 9808 | - | - | 1443132455Sep 24 2015 | 1688332611Jul 02 2023 |
 | Terror Revelation | Trilobyte | Trilobyte | MSX2
| Under development | - | 9651 | - | - | 1359131730Jan 25 2013 | 1547422624Jan 13 2019 |
 | Terrorpods | Melbourne House | Dro Soft | MSX
| 1989 | - | 13459 | - | - | 1177974000May 01 2007 | 1779400116May 21 2026 |
| The Godzilla vs. 3 Major Monsters | Bandai | - | MSX
| 1984 | 380 | 30371 | - | - | 1165162825Dec 03 2006 | 0Jan 01 1970 |
| The Great Escape | Pentacour | - | MSX
| Under development | - | 10932 | - | - | 1441415549Sep 05 2015 | 1441415817Sep 05 2015 |
 | The Havoc | Traposoft | - | MSX2
| 1990 | 52 | 10457 | - | - | 1185490766Jul 26 2007 | 0Jan 01 1970 |
 | The Living Daylights Alta tensión | Walking Circles Software | - | MSX
| 1987 | 80 | 15746 | - | - | 1218853547Aug 16 2008 | 1375376703Aug 01 2013 |
| The Ninja Warriors
| Virgin Games | - | MSX
| 1989 | - | 7917 | - | - | 1318799398Oct 16 2011 | 0Jan 01 1970 |
 | The Police Story ポリスストーリー Jackie Chan in "The Police Story" | Pony Canyon | Pony Canyon | MSX
| 1985 | 69 | 14802 | - | - | 1154512570Aug 02 2006 | 1480588820Dec 01 2016 |
 | The Protector プロテクター Jackie Chan in "The Protector" Protector | Pony Canyon | Pony Canyon | MSX
| 1985 | 92 | 22271 | - | - | 1200326434Jan 14 2008 | 1480584966Dec 01 2016 |
 | The Running Dragon | Polysoft | - | MSX2
| 1989 | 41 | 15584 | - | - | 1178654628May 08 2007 | 0Jan 01 1970 |
 | The Running Man | Grandslam Entertainments | - | MSX
| 1990 | 59 | 13599 | - | - | 1154465071Aug 01 2006 | 0Jan 01 1970 |
 | The Three Dragon Story 용의 전설 | Zemina | Zemina | MSX
| 1989 | 71 | 15823 | - | - | 1226707200Nov 15 2008 | 1752100590Jul 09 2025 |
 | The Wig | MSX Magazine (Japan) | - | MSX2
| 1989 | 87 | 14122 | - | - | 1209555845Apr 30 2008 | 0Jan 01 1970 |
 | Thexder テグザー Chexder | Compile | Game Arts | MSX
| 1986 | 150 | 25892 | - | - | 1155078000Aug 09 2006 | 1780742550Jun 06 2026 |
 | Thunder Blade Thunderblade | Tiertex
U.S. Gold | ERBE Software | MSX
| 1989 | 89 | 15769 | - | - | 1159570800Sep 30 2006 | 1779663450May 24 2026 |
 | Thunder Storm サンダーストーム | Data East | Victor | MSX
| 1985 | - | 8548 | - | - | 1521720424Mar 22 2018 | 1521720602Mar 22 2018 |
 | Time Out | New Frontier | Zafiro | MSX
| 1988 | - | 11413 | - | - | 1159138800Sep 25 2006 | 1782051513Jun 21 2026 |
 | Time Rider | Eurosoft | Eurosoft | MSX
| 1988 | - | 16507 | - | - | 1141344000Mar 03 2006 | 1782052588Jun 21 2026 |
 | Toi Acid Game | Iber Soft | MCM Software | MSX
| 1989 | - | 23296 | - | - | 1177974000May 01 2007 | 1782074687Jun 21 2026 |
 | Tokyo Gang | Mar Entertainments | G.L.L. | MSX
| 1990 | - | 13224 | - | - | 1318806000Oct 17 2011 | 1782075387Jun 21 2026 |
 | Trantor - The Last Stormtrooper | Probe Software | Go! | MSX
| 1988 | - | 12562 | - | - | 1260316800Dec 09 2009 | 1782922940Jul 01 2026 |
 | Trogloditas | Kotai | - | MSX
| 1989 | 49 | 13589 | - | - | 1295384259Jan 18 2011 | 0Jan 01 1970 |
 | Tuma-7 | Delta Software | - | MSX
| 1990 | 52 | 14357 | - | - | 1318844036Oct 17 2011 | 0Jan 01 1970 |
 | Turbo MSX Vol.8 - Phase Moon | GEASA | GEASA | MSX
| Unknown | - | 8556 | - | - | 1488582538Mar 03 2017 | 1488587988Mar 04 2017 |
 | Turrican | Giuseppe Pintus | - | MSX
| Under development | - | 9040 | - | - | 1642733646Jan 21 2022 | 1668120960Nov 10 2022 |
 | Turtle Mania | MSX-Studio Agnes Müller | Omnium | MSX2
MSX2+
MSX turbo R
| 1992 | 38 | 16086 | - | - | 1209377179Apr 28 2008 | 1602581967Oct 13 2020 |
 | Twinkle Star | MSX Magazine (Japan) | - | MSX2
| 1990 | 118 | 14038 | - | - | 1195385721Nov 18 2007 | 0Jan 01 1970 |
| UFO | Paper Soft | Paper Soft | MSX
| 1985 | - | 7058 | - | - | 1659650409Aug 04 2022 | 1659653424Aug 04 2022 |
 | Uchugame | K. Narita | - | MSX turbo R
| 1993 | 56 | 13154 | - | - | 1306248957May 24 2011 | 0Jan 01 1970 |
 | Undeadline アンデッドライン | T&E Soft | T&E Soft | MSX turbo R
MSX2
| 1989 | 428 | 27750 | 1 | 80% | 1196208000Nov 28 2007 | 1780765466Jun 06 2026 |
 | Valis 夢幻戦士ヴァリス The Fantasm Soldier Mugen Senshi Valis - The Fantasm Soldier | Telenet Japan | Telenet Japan | MSX
| 1986 | 153 | 21522 | - | - | 1200310498Jan 14 2008 | 1490134028Mar 21 2017 |
 | Vampire Killer 悪魔城ドラキュラ Akumajō Dracula Castlevania | Konami | Konami | MSX2
| 1986 | - | 28731 | - | - | 1230336000Dec 27 2008 | 1768149408Jan 11 2026 |
 | Vaxol ヴァクソル | Heart Soft | - | MSX
| 1987 | 53 | 20988 | - | - | 1178038515May 01 2007 | 0Jan 01 1970 |
 | Vigilante | Clover | - | MSX
| 1990 | 67 | 11353 | - | - | 1297896631Feb 16 2011 | 1375376703Aug 01 2013 |
 | Vortex Raider | Dis'Pair | Premium III Software Distribution | MSX
| 1988 | - | 16116 | - | - | 1159570800Sep 30 2006 | 1783819929Jul 12 2026 |
 | Wells & Fargo | Topo Soft | ERBE Software | MSX
| 1988 | - | 16691 | - | - | 1177974000May 01 2007 | 1784662223Jul 21 2026 |
 | Who Dares Wins II 8つの戦場 Who Dares Wins 2 Mercenario | Alligata | Alligata | MSX
| 1987 | - | 28608 | 1 | 69% | 1196208000Nov 28 2007 | 1784658036Jul 21 2026 |
 | Wilco | Manhattan Transfer | Manhattan Transfer | MSX
| Unknown | 34 | 20339 | - | - | 1318849295Oct 17 2011 | 1483534975Jan 04 2017 |
 | Wolf of the Battlefield Commando | Capcom | ASCII Corporation | MSX
| 1985 | 92 | 21353 | - | - | 1165219794Dec 04 2006 | 1375376703Aug 01 2013 |
 | Wonder Boy in Monster Land ワンダーボーイII・モンスターランド | Nippon Dexter | Nippon Dexter | MSX
| Unreleased | - | 239 | - | - | 1751155200Jun 29 2025 | 1751224255Jun 29 2025 |
 | Wrangler | Indescomp | - | MSX
| 1985 | 46 | 12064 | - | - | 1223727510Oct 11 2008 | 1375376703Aug 01 2013 |
 | XeGrader ぜグレイダー | Skipmore
Tokihiro Naito | BOOTH | MSX2
| 2025 | - | 360 | - | - | 1745884800Apr 29 2025 | 1752263194Jul 11 2025 |
 | Xeros | - | - | MSX
| Unknown | 47 | 11029 | - | - | 1333666681Apr 05 2012 | 1375376703Aug 01 2013 |
 | Yonder Blade Pa-Su Yonder Blade
| Hideo Nakata (Nakata Soft) | MSX･FAN | MSX
| 1989 | - | 8350 | - | - | 1341696645Jul 07 2012 | 1693519769Aug 31 2023 |
 | Youma Korin 妖魔降臨 | Nippon Dexter | Nippon Dexter | MSX2
| 1989 | 140 | 15334 | - | - | 1196208000Nov 28 2007 | 1752102163Jul 10 2025 |
 | Yuureikun 幽霊君 Mr. Ghost | System Sacom | System Sacom | MSX2
| 1989 | 190 | 23296 | 1 | 83% | 1215211201Jul 04 2008 | 1517783659Feb 04 2018 |
 | Zoom 909 ズーム９０９ | SEGA | Pony Canyon | MSX
| 1985 | 30 | 13865 | - | - | 1230569046Dec 29 2008 | 1702543820Dec 14 2023 |
